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& Randall, V

The dysregulation of glycolysis in these cells has been identified as a significant initiator of neuronal impairments in AD [66]

10.1016/j.tranon.2025.102380 195 ZhaoH.XuY.ShangH

10:e2960

Studies have also demonstrated that mice expressing ApoE4 in tauopathy models exhibit more severe tau-induced neurodegeneration compared to other isoforms, while mice lacking ApoE are protected from this effect (Shi et al., 2017)